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 Post subject: MMC causes dry eye
PostPosted: Mon May 29, 2006 2:21 pm 
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Joined: Sat Nov 26, 2005 1:23 pm
Posts: 2080
Dry Eye After Photorefractive
Keratectomy With Adjuvant Mitomycin C

George D. Kymionis, MD, PhD; Nikolaos S. Tsiklis, MD;
Harilaos Ginis, PhD; Vasilios F. Diakonis, MD;
Ioannis Pallikaris, MD, PhD

ABSTRACT

PURPOSE: To report a patient with dry eye after bilateral photorefractive
keratectomy (PRK) with mitomycin C treatment in one eye.

METHODS: A 29-year-old woman underwent PRK for moderate
myopia. The left eye was randomly assigned and intraoperative
topical mitomycin C was administered. The right (control) eye was
treated with intraoperative corticosteroid only.

RESULTS: The patient developed dry eye symptoms and superfi -
cial punctuate keratopathy in the eye treated with mitomycin C.
Fifteen months after surgery no improvement was noted.
CONCLUSIONS: Photorefractive keratectomy with mitomycin C
treatment could induce or exacerbate dry eye.

[J Refract Surg. 2006;22:511-513.]

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 Post subject:
PostPosted: Fri May 18, 2007 3:42 am 
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Joined: Sat May 12, 2007 9:18 pm
Posts: 45
Location: Studio City, CA
I'm curious. What exactly did the mitomycin C do?
Did it kill goblet cells, damage blood vessels or what?
:?


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