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 Post subject: Systemic meds linked to dry eye syndrome
PostPosted: Fri Feb 23, 2007 12:35 pm 

Joined: Sat Nov 26, 2005 1:23 pm
Posts: 2080
I posted this article for educational purposes. Those of us who suffer from post-LASIK dry eye need to know that certain medications can exacerbate the condition.


OSN SuperSite Top Story 2/21/2007

Dry eye syndrome may be more widespread than predicted, linked to systemic medications

DANA POINT, Calif. ? Dry eye syndrome could be on the rise, and it may be correlated with the use of common systemic medications, according to a physician speaking at the Ocular Drug and Surgical Therapy Update meeting here.

"There does exist a pharmacologic explanation for many dry eye patients who take systemic medicines," Michael S. Conners, MD, PhD, said. "I want you to see what a tremendous impact these medications are having on tear production in our patients.

"Dry eye is more prevalent with age, and medication use is more prevalent with age. Many systemic medications exacerbate dry eye. Of the most-prescribed medications prescribed in 2005, 43% were associated with worsening dry eye syndrome. We are going to see these medications on a daily basis," Dr. Conners said.

Some drug categories associated with reduced tear production include antispasmodics, antiemetics, antihistamines, tricyclic antidepressants, selective serotonin reuptake inhibitors and antipsychotics.

He said the systemic medications have an effect on the parasympathetic and sympathetic nervous system, which control the lacrimal acini and their pump functions.

"If you block with anticholinergic (antimuscarinic) agents, you decrease tear production," he said.

One to two patients out of every 10 will statistically and epidemiologically carry a diagnosis of dry eye, Dr. Conners noted.

"The goal would be, as eye care providers, if we could educate the primary care physicians and subspecialists regarding better choices when available, we could maybe impact the effects on dry eye," Dr. Conners said.

"If we can modify these comorbidities, we can lessen their impact on dry eye and improve the quality of life of our patients," he said.

Broken Eyes

"The price good men pay for indifference to public affairs is to be ruled by evil men." Plato

 Post subject: Antidepressents patients may need for LASIK crisis dry eyes
PostPosted: Fri Mar 02, 2007 8:19 pm 

Joined: Mon Nov 14, 2005 4:28 pm
Posts: 643
It is well known that antidepressents may not be well tolerated by patients who have had corneal refractive surgery because they often exacerbate dry eye caused by surgical nerve damage and they also exacerbate visual problems in large pupil patients.

These drugs are often sorely needed by patients who must face that they have been permanently visually compromised by a LASIK surgeon and must learn to adjust to a life with reduced and/or reduced quality vision.

LASIK is full of catch-22's. The drugs that may help you are not well tolerated because you have had corneal refractive surgery. The hard contacts that may help you are not well tolerated because you've had corneal refractive surgery.

The surgeon who you trusted to care for your vision may not be willing to retain you in his/her practice because patients in the waiting room with bad LASIK outcomes are bad for business. Imagine the optimistic patient coming in for a screening next to a patient that was recently badly butchered.

One young man walked into a center where TWO patients who were badly butchered were in the waiting room. He decided not to have the surgery :wink:

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