http://www.escrs.org/PUBLICATIONS/EUROT ... ionand.pdf
"Dr Wilson, professor of ophthalmology,
and director of cornea research at the
Cole Eye Institute in the Cleveland Clinic,
Cleveland Ohio
There are significant limitations, he said,
to the whole principle of custom ablations.
?Wavefront-guided ablations do not treat
all the higher order aberrations and they
induce some postoperative higher order
aberrations. Every time we do a refractive
procedure whether it is LASEK or PRK or
LASIK, we have some induction of higher
order aberrations and this is true even
with custom ablations.?
Dr Wilson said there are daily
fluctuations in the wavefront aberrations
and aberrations vary with pupil size.
Aberrations, he said, change with age and
variations in aberrations occur with
accommodation. He also pointed out that
wound healing and biomechanical changes
alter aberrations after surgery.
?When you add all of these together,
how can this possibly be a meaningful
application?"